diff --git a/liberapay/models/exchange_route.py b/liberapay/models/exchange_route.py
index 33edb0e15..02120b1de 100644
--- a/liberapay/models/exchange_route.py
+++ b/liberapay/models/exchange_route.py
@@ -223,6 +223,22 @@ def set_as_default(self):
                 id=self.id, network=self.network
             ))
 
+    def set_as_default_for(self, currency):
+        with self.db.get_cursor() as cursor:
+            cursor.run("""
+                UPDATE exchange_routes
+                   SET is_default_for = NULL
+                 WHERE participant = %(p_id)s
+                   AND is_default_for = %(currency)s;
+                UPDATE exchange_routes
+                   SET is_default_for = %(currency)s
+                 WHERE participant = %(p_id)s
+                   AND id = %(route_id)s
+            """, dict(p_id=self.participant.id, route_id=self.id, currency=currency))
+            self.participant.add_event(cursor, 'set_default_route_for', dict(
+                id=self.id, network=self.network, currency=currency,
+            ))
+
     def set_mandate(self, mandate_id):
         self.db.run("""
             UPDATE exchange_routes
diff --git a/liberapay/models/participant.py b/liberapay/models/participant.py
index 2a7846848..5ef449bf1 100644
--- a/liberapay/models/participant.py
+++ b/liberapay/models/participant.py
@@ -2028,6 +2028,16 @@ def get_currencies_for(tippee, tip):
                 fallback_currency = 'USD'
             return fallback_currency, accepted
 
+    @cached_property
+    def donates_in_multiple_currencies(self):
+        return self.db.one("""
+            SELECT count(DISTINCT amount::currency) > 1
+              FROM current_tips
+             WHERE tipper = %s
+               AND amount > 0
+               AND renewal_mode > 0
+        """, (self.id,))
+
 
     # More Random Stuff
     # =================
diff --git a/liberapay/payin/cron.py b/liberapay/payin/cron.py
index b755e0eab..50eeac7aa 100644
--- a/liberapay/payin/cron.py
+++ b/liberapay/payin/cron.py
@@ -264,7 +264,8 @@ def execute_scheduled_payins():
                     AND r.status = 'chargeable'
                     AND r.network::text LIKE 'stripe-%%'
                     AND ( sp.amount::currency = 'EUR' OR r.network <> 'stripe-sdd' )
-               ORDER BY r.is_default NULLS LAST
+               ORDER BY r.is_default_for = sp.amount::currency DESC NULLS LAST
+                      , r.is_default DESC NULLS LAST
                       , r.ctime DESC
                   LIMIT 1
                ) r ON true
diff --git a/sql/branch.sql b/sql/branch.sql
new file mode 100644
index 000000000..3162afb92
--- /dev/null
+++ b/sql/branch.sql
@@ -0,0 +1 @@
+ALTER TABLE exchange_routes ADD COLUMN is_default_for currency;
diff --git a/www/%username/giving/pay/stripe/%payin_id.spt b/www/%username/giving/pay/stripe/%payin_id.spt
index 66ae4d4ad..e1db9b691 100644
--- a/www/%username/giving/pay/stripe/%payin_id.spt
+++ b/www/%username/giving/pay/stripe/%payin_id.spt
@@ -87,19 +87,20 @@ if request.method == 'POST':
                 body.word('token'), one_off, payin_amount, owner_info, return_url
             )
             route = ExchangeRoute.attach_stripe_source(payer, source, one_off)
-            if body.parse_boolean('set_as_default', default=False):
-                route.set_as_default()
         elif 'stripe_pm_id' in body:
             one_off = body.get('keep') != 'true'
             pm = stripe.PaymentMethod.retrieve(body.word('stripe_pm_id'))
             route = ExchangeRoute.attach_stripe_payment_method(payer, pm, one_off)
-            if body.parse_boolean('set_as_default', default=False):
-                route.set_as_default()
         else:
             route = ExchangeRoute.from_id(payer, body.get_int('route'), _raise=False)
             if route is None:
                 raise response.invalid_input(body.get('route'), 'route', 'body')
             route.sync_status()
+        if body.parse_boolean('set_as_default', default=False):
+            route.set_as_default()
+        set_as_default_for = body.get_currency('set_as_default_for', None)
+        if set_as_default_for:
+            route.set_as_default_for(set_as_default_for)
 
     except stripe.error.StripeError as e:
         raise response.error(e.http_status or 500, _(
@@ -188,7 +189,20 @@ elif payin_id:
         """, (payin.id,)) > 0
     )
 
-else:
+tippees = request.qs.parse_list('beneficiary', int, default=None)
+if tippees:
+    tips = [
+        tip for tip in payer.get_tips_to(tippees)
+        if tip.tippee_p.payment_providers & STRIPE_BIT > 0
+    ]
+    if len(set(tip.amount.currency for tip in tips)) != 1:
+        raise response.invalid_input(tippees, 'beneficiary', 'querystring')
+    payment = PayinProspect(payer, tips, 'stripe')
+    for tip in tips:
+        if payment.currency not in tip.tippee_p.accepted_currencies_set:
+            raise response.redirect(payer.path(
+                'giving/pay?redirect_reason=unaccepted_currency'
+            ))
     routes = website.db.all("""
         SELECT r
           FROM exchange_routes r
@@ -196,10 +210,11 @@ else:
            AND r.status = 'chargeable'
            AND r.network::text LIKE %s
            AND (r.one_off IS FALSE OR r.ctime > (current_timestamp - interval '6 hours'))
-      ORDER BY r.is_default NULLS LAST
+      ORDER BY r.is_default_for = %s DESC NULLS LAST
+             , r.is_default DESC NULLS LAST
              , r.network = 'stripe-sdd' DESC
              , r.id DESC
-    """, (payer.id, 'stripe-' + (payment_type or '%')))
+    """, (payer.id, 'stripe-' + (payment_type or '%'), payment.currency))
     if routes:
         route = None
         while routes:
@@ -212,21 +227,6 @@ else:
         del route
     if not payment_type:
         response.redirect(payer.path('giving/pay'))
-
-tippees = request.qs.parse_list('beneficiary', int, default=None)
-if tippees:
-    tips = [
-        tip for tip in payer.get_tips_to(tippees)
-        if tip.tippee_p.payment_providers & STRIPE_BIT > 0
-    ]
-    if len(set(tip.amount.currency for tip in tips)) != 1:
-        raise response.invalid_input(tippees, 'beneficiary', 'querystring')
-    payment = PayinProspect(payer, tips, 'stripe')
-    for tip in tips:
-        if payment.currency not in tip.tippee_p.accepted_currencies_set:
-            raise response.redirect(payer.path(
-                'giving/pay?redirect_reason=unaccepted_currency'
-            ))
     ask_for_postal_address = (
         payment_type == 'sdd' or
         len(tips) == 1 and
@@ -509,10 +509,18 @@ title = _("Funding your donations")
                 <input type="checkbox" name="keep" value="true" checked />
                 {{ _("Remember the card number for next time") }}
             </label><br>
+            % if payer.donates_in_multiple_currencies
+            <label>
+                <input type="checkbox" name="set_as_default_for" value="{{ payment.currency }}" checked />
+                {{ _("Use this payment instrument by default for future payments in {currency}",
+                     currency=Currency(payment.currency)) }}
+            </label>
+            % else
             <label>
                 <input type="checkbox" name="set_as_default" value="true" checked />
                 {{ _("Use this payment instrument by default for future payments") }}
             </label>
+            % endif
             <br><br>
         </fieldset>
         % elif payment_type == 'sdd'
diff --git a/www/%username/routes/index.spt b/www/%username/routes/index.spt
index b916f3482..d43d476ce 100644
--- a/www/%username/routes/index.spt
+++ b/www/%username/routes/index.spt
@@ -19,6 +19,17 @@ if request.method == 'POST':
         route = ExchangeRoute.from_id(participant, request.body.get_int('set_as_default'), _raise=False)
         if route:
             route.set_as_default()
+    elif 'set_as_default_for' in request.body:
+        try:
+            route_id, currency = request.body['set_as_default_for'].split(':')
+            route_id = int(route_id)
+            if currency not in constants.CURRENCIES:
+                raise ValueError(currency)
+        except ValueError:
+            raise response.invalid_input(request.body['set_as_default_for'], 'set_as_default_for', 'body')
+        route = ExchangeRoute.from_id(participant, route_id, _raise=False)
+        if route:
+            route.set_as_default_for(currency)
     else:
         raise response.error(400, "no known action found in request body")
     form_post_success(state)
@@ -100,7 +111,16 @@ title = _("Payment Instruments")
                     <span class="text-muted">({{ locale.currencies.get(route.currency, route.currency) }})</span>
                 % endif
                 % if route.is_default
-                    &nbsp; <span class="label label-primary">{{ _("default") }}</span>
+                    &nbsp; <span class="label label-primary" title="{{ _(
+                        'This instrument is used by default.'
+                    ) }}">{{ _("default") }}</span>
+                % elif route.is_default_for
+                    &nbsp; <span class="label label-primary" title="{{ _(
+                        'This instrument is used by default for payments in {currency}.',
+                        currency=Currency(route.is_default_for)
+                    ) }}">{{ _(
+                        "default for {currency}", currency=route.is_default_for
+                    ) }}</span>
                 % endif
                 % if route.status == 'pending'
                     &nbsp; <span class="label label-warning">{{ _("pending") }}</span>
@@ -159,6 +179,16 @@ title = _("Payment Instruments")
                 <button class="btn btn-danger btn-xs" name="remove" value="{{ route.id }}">{{ _("Remove") }}</button>
             % if not route.is_default
                 <button class="btn btn-primary btn-xs" name="set_as_default" value="{{ route.id }}">{{ _("Set as default") }}</button>
+                % if last_payin and participant.donates_in_multiple_currencies
+                    <button class="btn btn-primary btn-xs"
+                            name="set_as_default_for" value="{{ route.id }}:{{ last_payin.amount.currency }}"
+                            title="{{ _(
+                                'Use this instrument by default for payments in {currency}.',
+                                currency=Currency(last_payin.amount.currency)
+                            ) }}">{{ _(
+                        "Set as default for {currency}", currency=last_payin.amount.currency
+                    ) }}</button>
+                % endif
             % endif
             </span>
         </div>